Peer-reviewed Publications (counter-chronological order)
- LRRK2 at the Crossroad of Aging and Parkinson's Disease. Hur EM, Lee BD (2021) Genes (Basel) 12(4):505.
- Modulation of Nogo receptor 1 expression orchestrates myelin-associated infiltration of glioblastoma. Hong JH, Kang S, Sa JK, Park G, Oh YT, Kim TH, Yin J, Kim SS, D'Angelo F, Koo H, You Y, Park S, Kwon HJ, Kim CI, Ryu H, Lin W, Park EJ, Kim YJ, Park MJ, Kim H, Kim MS, Chung S, Park CK, Park SH, Kang YH, Kim JH, Saya H, Nakano I, Gwak HS, Yoo H, Lee J, Hur EM, Shi B, Nam DH, Iavarone A, Lee SH, Park JB (2021) Brain 144(2):636-654.
- Comparing axon regeneration in male and female mice after peripheral nerve injury. Jang EH, Bae YH, Yang EM, Gim Y, Suh HJ, Kim S, Park SM, Park JB, Hur EM (2021) J Neurosci Res. doi: 10.1002/jnr.24955.
- A Role of Microtubules in Oligodendrocyte Differentiation. Lee BY, Hur EM (2020) Int J Mol Sci 21(3):1062.
- LRRK2 and membrane trafficking: nexus of Parkinson's disease. Hur EM, Jang EH, Jeong GR, Lee BD (2019) BMB Rep 52(9):533-539.
- Structural and molecular basis for katanin-mediated severing of glutamylated microtubules. Shin SC^, Im SK^, Jang EH, Jin KS, Hur EM*, Kim EE* (2019) Cell Rep 26(5):1357-1367. (^Co-first, *Co-correspondence)
- Dedifferentiated Schwann cells secrete progranulin that enhances the survival and axon growth of motor neurons. Hyung S^, Im SK^, Lee BY, Shin J, Park JC, Lee C, Francis Suh JK, Hur EM (2019) GLIA 67(2):360-375. (^Co-first)
- Brain injury induces HIF-1α-dependent transcriptional activation of LRRK2 that exacerbates brain damage. Bae YH, Joo H, Bae J, Hyeon SJ, Her S, Ko E, Choi HG, Ryu H, Hur EM, Bu Y, Lee BD (2018) Cell Death Dis 9(11):1125.
- Dysregulated phosphorylation of Rab GTPases by LRRK2 induces neurodegeneration. Jeong GR^, Jang EH^, Bae JR, Jun S, Kang HC, Park CH, Shin JH, Yamamoto Y, Tanaka-Yamamoto K, Dawson VL, Dawson TM, Hur EM*, Lee BD* (2018) Mol Neurodegener 13(1):8. (^Co-first, *Co-correspondence)
- Ultrasensitive terahertz molecule sensor for observation of photoinduced conformational change in rhodopsin-nanovesicles. Lee DK, Yang H, Song HS, Park B, Hur EM, Kim JH, Park TH, Seo M (2018) Sensors and Actuators B: Chemcial 273(10):1371-1375.
- Differential roles of glycogen synthase kinase 3 subtypes alpha and beta in cortical development. Ma YX, Wang Xl, Chen JQ, Li B, Hur EM*, Saijilafu* (2017) Front Mol Neurosci 10:391. (*Co-correspondence)
- Functional characterization of resting and adenovirus-Induced reactive astrocytes in three-dimensional culture. Woo J^, Im SK^, Chun H, Jung SY, Oh SJ, Choi N, Lee CJ, Hur EM (2017) Exp Neurobiol 26(3): 158-167. (^Co-first)
- Anisotropically organized three-dimensional culture platform for reconstruction of a hippocampal neural network. Kim SH^, Im SK^, Oh SJ^, Jeong S, Yoon ES, Lee CJ, Choi N*, Hur EM* (2017) Nat Commun 8:14346. (Featured Article) (^Co-first, *Co-correspondence)
- Effects of microtubule stabilization by epothilone B depend on the type and age of neurons. Jang EH, Sim A, Im SK, Hur EM (2016) Neural Plast 2016:5056418.
- Korea Brain Initiative: Integration and Control of Brain Functions. Jeong SJ, Lee H, Hur EM, Choe Y, Koo JW, Rah JC, Lee KJ, Lim HH, Sun W, Moon C, Kim K (2016) Neuron 92(3):607-611.
- Inflammatory signals induce the expression of tonicity-responsive enhancer binding protein (TonEBP) in microglia. Jeong GR, Im SK, Bae YH, Park ES, Jin BK, Kwon HM, Lee BJ, Bu Y, Hur EM*, Lee BD* (2016) J Neuroimmunol 295-296:21-29 (*Co-correspondence)
- DSCR1 is required for both axonal growth cone extension and steering. Wang W, Rai A, Hur EM, Smilansky Z, Chang KT, Min KT (2016) J Cell Biol 213(4):451-462.
- ACT-PRESTO: Rapid and consistent tissue clearing and labeling method for 3D imaging. Lee E, Choi J, Jo Y, Kim JY, Jang YJ, Lee HM, Kim SY, Lee HJ, Cho K, Jung N, Hur EM, Jeong SJ, Moon C, Choe Y, Rhyu IJ, Kim H, Sun W (2016) Sci Rep 6:18631.
- Coculture of primary motor neurons and schwann cells as a model for in vitro myelination. Hyung S, Lee BY, Park JC, Kim J, Hur EM, Francis Suh JK (2015) Sci Rep 5:15122.
- Pigment epithelium-derived factor expression induced by EGFRvIII promotes self-renewal and tumor progression of glioma stem cells. Yin J, Park G, Kim TH, Hong JH, Kim YJ, Jin X, Kang S, Jung JE, Kim JY, Yun H, Lee JE, Kim M, Chung J, Kim H, Nakano I, Gwak HS, Yoo H, Yoo BC, Kim JH, Hur EM, Lee J, Lee SH, Park MJ, Park JB (2015) PLoS Biol 13(5):e1002152.
- Microtubule-targeting agents enter the central nervous system (CNS): double-edged swords for treating CNS injury and disease. Hur EM, Lee BD (2014) Int Neurourol J 18(4):171-178.
- Direct interaction and functional coupling between human 5-HT6 receptor and the light chain 1 subunit of the microtubule-associated protein 1B (MAP1B-LC1). Kim SH, Kim DH, Lee KH, Im SK, Hur EM, Chung KC, Rhim H (2014) PLoS One 9(3):e91402.
- PI3K-GSK3 pathway regulates mammalian axon regeneration by inducing the expression of smad1. Saijilafu^, Hur EM^, Jiao Z, Liu CM, Zhou FQ (2013) Nat Commun 4: 2690. (^Co-first)
- DJ-1 promotes angiogenesis and osteogenesis by activating FGF receptor-1 signaling. Kim JM, Shin HI, Cha SS, Lee CS, Hong BS, Lim S, Jang HJ, Kim J, Yang YR, Kim YH, Yun S, Rijal G, Lee-Kwon W, Seo JK, Gho YS, Kim KT, Ryu SH, Hur EM, Suh PG (2012) Nat Commun 3:1296.
- Slit2 inactivates GSK3β to signal neurite outgrowth inhibition. Byun J, Kim BT, Kim YT, Jiao Z, Hur EM*, Zhou FQ* (2012) PLoS One 7(12):e51895. (*Co-correspondence)
- Growing the growth cone: remodeling the cytoskeleton to promote axon regeneration. Hur EM, Saijilafu, Zhou FQ (2012) Trends Neurosci 35(3):164-174. (Cover featured)
- Desipramine inhibits histamine H1 receptor-induced Ca2+ signaling in rat hypothalamic cells. Kang JA, Lee K, Lee KM, Cho S, Seo J, Hur EM, Park CS, Baik JH, Choi SY (2012) PLoS One. 7(4):e36185.
- Coordinating Gene Expression and Axon Assembly to Control Axon Growth: Potential Role of GSK3 Signaling. Liu CM, Hur EM, Zhou FQ (2012) Front Mol Neurosci 5:3.
- Genetic dissection of axon regeneration via in vivo electroporation of adult mouse sensory neurons. Saijilafu, Hur EM, Zhou FQ (2011) Nat Commun 2:543.
- GSK3 controls axon growth via CLASP-mediated regulation of growth cone microtubules. Hur EM, Saijilafu, Lee BD, Kim SJ, Xu WL, Zhou FQ (2011) Genes Dev 25(18):1968-1981.
- Engineering neuronal growth cones to promote axon regeneration over inhibitory molecules. Hur EM, Yang IH, Kim DH, Byun J, Saijilafu, Xu WL, Nicovich PR, Cheong R, Levchenko A, Thakor N, Zhou FQ (2011) Proc Natl Acad Sci U S A, 108(12):5057-5062.
- Role of GSK3 signaling in neuronal morphogenesis. Kim YT, Hur EM, Snider WD, Zhou FQ (2011) Front Mol Neurosci 4:48.
- GSK3 signalling in neural development. Hur EM, Zhou FQ (2010) Nat Rev Neurosci, 11(8):539-551. (Featured Article)
- A role of local signalling in the establishment and maintenance of the asymmetrical architecture of a neuron. Hur EM, Kim KT (2007) J Neurochem, 101(3):600-610.
- Involvement of protein kinase C-ε in activity-dependent potentiation of large dense-core vesicle exocytosis in chromaffin cells. Park YS, Hur EM, Choi BH, Kwak EY, Jun DJ, Park SJ, Kim KT (2006) J Neurosci, 26(35):8999-9005.
- Protein kinase Cδ-mediated proteasomal degradation of MAP kinase phosphatase-1 contributes to glutamate-induced neuronal cell death. Choi BH, Hur EM, Lee JH, Jun DJ, Kim KT (2006) J Cell Sci, 119(Pt 7):1329-1340.
- Norepinephrine activates store-operated Ca2+ entry coupled to large conductance Ca2+-activated K+ channels in rat pinealocytes. Lee SY, Choi BH, Hur EM, Lee JH, Lee SJ, Lee CO, Kim KT. (2006) Am J Physiol-Cell Physiology, 290(4):C1060-C1066.
- Activity-dependent potentiation of the large-dense core vesicle release is modulated by MAP kinase signaling. Park YS, Jun DJ, Hur EM, Lee SK, Suh BS, Kim KT (2006) Endocrinology, 147(3):1349-1356. (Cover featured).
- N-(4-Trifluoromethylphenyl)amide group of the synthetic histamine receptor agonist inhibits nicotinic acetylcholine receptor-mediated catecholamine secretion. Kim DC, Park YS, Jun DJ, Hur EM, Kim SH, Choi BH, Kim KT (2006) Biochem Pharmacol, 71(5):670-682.
- Inhibition of store-operated calcium entry-mediated superoxide generation by histamine trifluoromethyltoluide independent of histamine receptors. Kim DC, Lee SY, Jun DJ, Kim SH, Lee JH, Hur EM, Baek NI, Kim KT. (2005) Biochem Pharmacol, 70(11):1613-1622.
- Leumorphin has an anti-apoptotic effect by activating epidermal growth factor receptor (EGFR) kinase in rat pheochromocytoma PC12 cells. Lee BD, Kim S, Hur EM, Park YS, Kim YH, Lee TG, Kim KT, Suh PG, Ryu SH. (2005) J Neurochem, 95(1):56-67.
- Junctional membrane inositol 1,4,5-trisphosphate receptor complex coordinates sensitization of the silent EGF-induced Ca2+ signaling. Hur EM, Park YS, Huh YH, Yoo SH, Woo KC, Choi BH, Kim KT. (2005) J Cell Biol, 169(4):657-667. (Featured Article)
- Sensitization of epidermal growth factor (EGF)-induced signaling by bradykinin is mediated by c-Src: implications for a role of lipid microdomains. Hur EM, Park YS, Lee BD, Jang IH, Kim HS, Kim TD, Suh PG, Ryu SH, Kim KT. (2004) J Biol Chem, 279(7): 5852-5860.
- The direct interaction of phospholipase C-γ1 with phospholipase D2 is important for epidermal growth factor (EGF) signaling. Jang IH, Lee S, Park JB, Kim JH, Lee CS, Hur EM, Kim IS, Kim KT, Yagisawa H, Suh PG, Ryu SH. (2003) J Biol Chem, 278(20):18184-18190.
- Protein kinase A- and C-induced insulin release from Ca2+-insensitive pools. Lee IS, Hur EM, Suh BC, Kim MH, Koh DS, Rhee IJ, Ha H, Kim KT. (2003) Cell Signal, 15(5):529-537.
- G protein-coupled receptor signalling and cross-talk: achieving rapidity and specificity. Hur EM, Kim KT. (2002) Cell Signal, 14(5):397-405.
- Coupling of L-type voltage-sensitive calcium channels to P2X2 purinoceptors in PC12 cells. Hur EM, Park TJ, Kim KT. (2001) Am J Physiol Cell Physiol, 280(5):C1121-C1129.
- Nongenomic inhibition of catecholamine secretion by 17β-estradiol in PC12 cells. Kim YJ*, Hur EM*, Park TJ, Kim KT. (2000) *Equal contribution. J Neurochem, 74(6):2490-2496.
Patents
- STRETCHING APPARATUS AND METHOD FOR ALIGNING MICROFIBILRS (미국, US 9803167 B2) 등록일: 2017/10/31
- 희돌기아교세포 특이적 유전자 발현 조절 벡터 (대한민국, 10-1964875) 등록일: 2019/03/27
- 운동 뉴런의 생체외 배양 방법 및 운동 뉴런 배양용 조성물 (대한민국, 10-1898670) 등록일: 2018/09/07
- 희소돌기아교세포 분화용 조성물 및 이를 이용한 희소돌기아교세포 분화방법 (대한민국, 10-1878925) 등록일: 2018/07/10
- 뇌염증 진단용 바이오마커 및 이의 용도 (대한민국, 10-1875788) 등록일: 2018/07/02
- 생체외에서 운동 뉴런의 배양 방법 및 그 배양 키트 (대한민국, 10-1748631) 등록일: 2017/06/13
- 마우스의 신경교세포 배양용 배지 조성물 및 마우스 신경교세포의 분화를 유도하는 방법 (대한민국, 10-1705698) 등록일: 2017/02/06
- 생체외에서 운동 신경세포의 배양 촉진을 위한 코엔자임 Q10을 포함하는 조성물 (대한민국, 10-1695429) 등록일: 2017/01/05
- 콜라젠 섬유를 정렬하기 위한 신장 장치 및 방법 (대한민국, 10-1661268) 등록일: 2016/09/23